He-man: Heroic Eternian warrior, and defender of the Universe.
Skeletor: Evil warlord and sorcerer who wants to control the universe.
The Sorceress: Guardian of Castle Grayskull, helps out He-man, is able to talk to He-man through time via telepathy.
Darius: Leader of the Galactic Council.
Hydron: Marine Commander, and Captian of the Starship Eternia.
Tartarus (a.k.a. Kayo): A fearless warrior.
Flipshot (a.k.a. Icarius): Space-age pilot, A young soldier who is able to control a set of Jet Wings.
Nocturna: Martial Artist, and a Warrior of the Night.
Vizar: Master of vision and mind power.
Insyzor (a.k.a. Tuskador): Warrior with powerful tusks.
Karatti: Hard-headed mutant Warrior.
Staghorn:
Flog (a.k.a. Brakk): Evil soldier in Skeletor's army, Skeletor's second-in-command.
Optikk: Evil warrior with an eyebal for a head.
Hoove: Hoofed warrior who helps Skeletor.
Spinwit:
Butthead:
Lizorr: Mutant lizard who helps Skeletor.
Slosh Head (a.k.a. Kalamarr): Cyborg with metal tentacles.
Earthquake (a.k.a. Quakke):
Artilla:
Sagitar: Galloping Battle Beast, has 4 arms and 2 legs, can run like a centaur.